Understanding the main route of drug entry in adult Fasciola hepatica: Further insights into closantel pharmacological activity

First report of closantel treatment failure against Fasciola hepatica in cattle

Control of Fasciola hepatica infection in livestock is based on annual treatment using flukicides such as triclabendazole, albendazole and closantel. However, triclabendazole resistant F. hepatica populations are emerging worldwide and resistance is emerging to albendazole, whereas it has until now never been described for closantel. In Sweden, a topical formulation containing a combination of ...

Understanding genetic diversity of the liver fluke Fasciola hepatica.

Economical breeding is important to obtain maximum gain from the breeding in the animal sector. The economic loss has to be eliminated or should be minimized. The liver fluke, Fasciola hepatica, present mostly in sheep and dairy cattle affect the yield of animals and even cause their death. To eliminate or minimize the impact of these parasites on the animals, it is important to understand the ...

Fasciola hepatica

18 The success of helminth parasites is partly related to their ability to modulate host immune 19 responses towards an anti-inflammatory/regulatory phenotype. This ability resides with the 20 molecules contained in the secretome of various helminths that have been shown to interact with 21 host immune cells and influence their function. Consequently, there exists a unique opportunity 22 to exp...

Further Observation on the Susceptibility of Different Species of Lymnaea Snails of Iran to Miracidia of Fasciola hepatica and Fasciola gigantica

The efficiency of diamphenethide against Fasciola hepatica in sheep